Occurrence of serological reactions for Leptospira spp. in donkeys and mules from Minas Gerais, Brazil.

Research concerning leptospirosis in donkeys and mules has been neglected around the world. Therefore, the aim of this study was to investigate the epidemiological situation of the prevalence of anti-Leptospira spp. antibodies in donkeys and mules from the state of Minas Gerais, Brazil. Blood serum samples were collected from 180 animals (109 donkeys and 71 mules) in two rural properties from the state of Minas Gerais, Brazil, and then submitted to a microscopic agglutination test (MAT). Urea and creatinine values were also quantified. Epidemiological variables such as age, breeding system, contact with other animal species, source of water and food, vaccination against leptospirosis, presence of reproductive alterations, and rodent control were also investigated. From 180 samples collected, 39 (21.67%) showed positive results in the MAT, at a dilution ≥ 1:100. Some animals were reactive for more than one serovar. The serovar Tarassovi was the most frequent (14.07%), followed by Hardjo (11.85%) and Wolffi (11.11%). There was a statistically significant difference between animals from 0 to 3 years of age reactive in the MAT in comparison to the other age groups. Most of the animals had urea and creatinine concentrations within the acceptable reference limit; however, there was a significant increase in creatinine levels in some of the test animals. The studied properties showed differences in some epidemiological aspects such as vaccination of the animals, presence of reproductive problems in the herd, and rodent control. Such aspects pointed as risk factors that may influence the frequency of positive serological results in property 1. The present study demonstrated that the prevalence of leptospirosis in donkeys and mules is high and several serovars are being maintained by these animals, representing a potential public health risk.

Genomic Surveillance of Monkeypox Virus, Minas Gerais, Brazil, 2022.

Phylogenetic analysis of 34 monkeypox virus genome sequences isolated from patients in Minas Gerais, Brazil, revealed initial importation events in early June 2022, then community transmission within the state. All generated genomes belonged to the B.1 lineage responsible for a global mpox outbreak. These findings can inform public health measures.

Experimental data of heat transfer nanofluids for trigeneration systems: viscosity at below-ambient temperatures.

The present work exhibits the dynamic viscosity profile data of three distinct nanofluids, at a constant shear stress, and within a range of temperatures that include below-ambient conditions (from -10 to 20 °C). The nanofluids were as follows. Nanofluid I: 30% ethylene glycol and 70% distilled water (v/v), with graphene (0.32% in mass); Nanofluid II: 30% engine coolant NBR 13705; ASTM D-3306; ASTM D-4985) and 70% distilled water (v/v), with graphene (0.2% in mass); and Nanofluid III: 30% engine coolant and 70% distilled water (v/v), with Multi-Walled Carbon Nanotubes (MWCNT) (0.2% in mass). The present work was motivated by the scarcity of experimental data on the temperature dependence of viscosity for graphene, MWCNT, and their hybrid nanofluids, at below-ambient temperatures.

O trem e a "senhorita espanhola": a epidemia de gripe em Diamantina, 1918 / The train and the "Spanish señorita": the flu epidemic in Diamantina, 1918

Resumo O artigo analisa a epidemia de gripe de 1918 em Diamantina, no interior de Minas Gerais. A partir de fontes bibliográficas e documentais, discute como o ramal ferroviário da Estrada de Ferro Vitória a Minas, inaugurado em 1914, contribuiu para a chegada da doença à cidade que, até então, era representada no discurso de suas elites como isolada e salubre. Aborda as imbricadas relações entre a expansão dos sistemas de transportes pelo interior do Brasil, o meio ambiente, o conhecimento científico e os processos saúde/doença.

Abstract The article analyzes the influenza epidemic in 1918 in Diamantina, a town in the Brazilian state of Minas Gerais. Bibliographic and documental sources are used to investigate the influence of the Vitória-Minas railroad (Estrada de Ferro Vitória a Minas), opened in 1914, on the arrival of the disease in the town, which had until then been represented in the discourse of its elites as insalubrious and isolated. The interrelations between the spread of transportation systems across Brazil, the environment, scientific knowledge, and health-disease processes are discussed.

Doenças de africanos, doença africana: transformações da quijila, entre a África centro-ocidental e as Minas Gerais, Brasil, séculos XVII e XVIII / Diseases of Africans, an African disease: transformations of quijila between Central West Africa and Minas Gerais, in Brazil, in the seventeenth and eighteenth centuries

Resumo Este artigo discute a origem da quijila/kijila na cultura centro-ocidental africana, mais particularmente no universo cultural dos imbangalas (jagas) e das populações ambundos e kimbundos, que viviam nas regiões portuguesas de Angola e do Congo, nos séculos XVII e XVIII. Em seguida, investiga como foi estruturado, compreendido e transformado o conceito de quijila tanto na África, basicamente um interdito alimentar, mas cujos significados e aplicações variam, quanto no Brasil, para onde foi transportado nos Setecentos, transformando-se numa doença que atacava os negros, especialmente os africanos de diversas origens, sendo enquadrada pelos médicos locais no universo da medicina hipocrática-galena vigente na época.

Abstract This article discusses the origin of quijila/kijila in Central West African culture, more particularly in the cultural universe of the Imbangala (Jaga) and the Ambundu and Kimbundu populations who lived in the Portuguese regions of Angola and the Congo in the seventeenth and eighteenth centuries. Following this, it investigates how the concept of quijila was structured, comprehended, and transformed, both in Africa, where it was basically a food prohibition, but whose applications and meanings varied; and in Brazil, to where it was transported in the 1700s, and where it transformed into a disease which attacked blacks, especially Africans of various origins, being framed as such in the Hippocratic-Galen universe characteristic of that time.

Epidemiological aspects of pediculosis by Pediculus humanus capitis (Phthiraptera: Pediculidae) in Minas Gerais: a systematic review / Aspectos epidemiológicos da pediculose por Pediculus humanus capitis (Phthiraptera: Pediculidae) em Minas Gerais: uma revisão sistemática

Abstract Background Head lice, or head pediculosis, is a parasitosis considered a serious public health problem that affects mainly resource-limited countries. Objective To describe epidemiological aspects of the pediculosis capitis in Minas Gerais, in Brazil. Method This systematic review was conducted through the standards established by the Preferred Reporting Items in Systematic Reviews and Metanalyses (PRISMA). PubMed, LILACS, and SciELO databases, as well as the gray literature, were searched. Results Nine of 1,167 studies were included, published between 1988 and 2019. These studies reported a total prevalence of parasitosis that ranged from 1.4% to 57.4%. The prevalence of head lice ranged from 0.0% to 66.7% for males and 2.3% to 57.4% for females, thus being higher in black-skinned people (1.4% to 40.3%). Regarding age, the highest prevalence was 10-12 years old (45.3%). As for the characteristics of the hair, there was a greater infestation in people with long (16.0% to 79.5%), wavy (0.0% to 44.7%), dark (0.0% to 36.6%), with low capillary density (35.4%), and thick hair (39.2%). Conclusion Head pediculosis affects both sexes, different ages, and races, representing an important health problem in Minas Gerais, not only due to the presence of ectoparasite but also to the secondary complications that can be generated from this parasitism.

Resumo Introdução A pediculose de cabeça é uma parasitose considerada um sério problema de saúde pública, afetando principalmente países com recursos limitados. Objetivo Descrever os aspectos epidemiológicos da pediculose de cabeça em Minas Gerais, Brasil. Método Revisão sistemática conduzida por meio dos padrões estabelecidos pelo Preferred Reporting Items in Systematic Reviews and Metanalyses (PRISMA). Foram pesquisadas as bases de dados PubMed, LILACS e SciELO, bem como a literatura cinza. Resultados Nove de 1.167 estudos foram incluídos, publicados entre 1988 e 2019. Relatou-se uma prevalência total da parasitose que variou de 1,4% a 57,4%. Ela variou de 0,0% a 66,7% para homens e 2,3% a 57,4% para mulheres, sendo maior em pessoas de cor negra (1,4% a 40,3%). Em relação à idade, a maior prevalência foi de 10 a 12 anos (45,3%). Quanto às características dos cabelos, houve maior infestação em pessoas com cabelos longos (16,0% a 79,5%), ondulados (0,0% a 44,7%), escuros (0,0% a 36,6%), com baixa densidade capilar (35,4%) e fios grossos (39,2%). Conclusão A pediculose atinge ambos os sexos, diferentes idades e raças, representando um importante problema de saúde em Minas Gerais, não só pela presença do ectoparasita, mas também pelas complicações secundárias que podem ser geradas desse parasitismo.

Psicologia educacional e escolar no "Jornal do Psicólogo" do CRP-MG / Educational and School Psychology in the "Journal of Psychologist" of CRP-MG / Psicología Educativa y Escolar en el "Jornal do Psicólogo" del CRP-MG

O Jornal do Psicólogo (JP) do Conselho Regional de Psicologia de Minas Gerais (CRP-MG) é uma fonte histórica sobre a interface Psicologia e Educação. Este estudo objetivou analisar as referências à Psicologia Educacional e Escolar (PEE) nesse periódico, elencando as citações sobre o profissional dessa área e a Educação brasileira, se essas referências são fundamentadas em pressupostos críticos, e quais são as contribuições veiculadas. Trata-se de uma pesquisa qualitativa e documental, cujo corpus foi constituído por 89 edições do jornal, das quais 35 traziam dados sobre a temática, que foram tratados através da análise de conteúdo. Os artigos selecionados para amostra denotam atuação do psicólogo numa perspectiva institucional e crítica, destacando-se a promoção de eventos, notícias sobre a criação da Associação Brasileira de Psicologia Escolar e Educacional e referência a profissionais mineiros. Os anos de 1999 a 2004 foram os mais produtivos com relação às publicações, corroborando a produção acadêmica crítica em PEE à época. Acredita-se que o decréscimo nos anos seguintes está relacionado à defesa do psicólogo como profissional da saúde. As gestões do CRP-MG influenciam os conteúdos do JP, mas, geralmente, a PEE é menos citada dentre as temáticas, como saúde mental e luta antimanicomial. As referências à Educação são pautadas nos Direitos Humanos e na concepção de escola democrática. O JP cumpre o papel de tratar as práticas do psicólogo na Educação numa perspectiva contrária à atuação individualizante e médico-clínica; porém, carece de uma maior divulgação da PEE a fim de fortalecer a imagem desse profissional como agente de transformação do contexto escolar. (AU)

The CRP-MG Newspaper entitled "Jornal do Psicólogo" (JP) is a historical source on the interface between Psychology and Education. This study aims to analyze the references to Educational and School Psychology (in Portuguese PEE) in this newspaper, listing quotes about the professional in this area and Brazilian Education and if these references are over critical bases: what are the criticisms and contributions conveyed. This is a qualitative and documentary research whose search data consists of 89 editions of the newspaper (35 bring data on the theme) treated through content analysis. The articles show the psychologist's performance in an institutional and critical perspective, highlighting the promotion of events, news about the creation of the Brazilian Association of School and Educational Psychology and the reference to professionals from Minas Gerais that area. From 1999 to 2004 the most productive years in terms of publications, corroborating the critical academic production in PEE at the time. The decrease in the following years is related to the defense of the psychologist as a health professional. The administrations of the CRP influence the contents of the newspaper, but, generally, PEE is less mentioned than other themes, such as mental health and psychiatric reform. References to Education are based on Human Rights and the concept of a democratic school. The newspaper JP fulfills the role of treating the psychologist's practices in Education in a perspective contrary to the individualizing and clinical medical model, however, it needs a greater dissemination of PEE to strengthen this professional as a school context agent of transformation. (AU)

El Periódico del Consejo Regional de Psicología del Estado de Minas Gerais (CRP-MG), llamado "Jornal do Psicólogo" (JP), es una fuente histórica sobre la interfaz Psicología y Educación. El estudio objetiva analizar las referencias a la Psicología Educativa y Escolar (PEE) en este periódico, enumerando las citas sobre el profesional de esta área y la Educación brasileña, cuestionando si estas se basan en supuestos críticos y cuáles son las críticas y sus contribuciones. Es una investigación cualitativa y documental, siendo elementos de investigación 89 ediciones, de las cuales 35 aportan datos sobre el tema, que fueron tratados a través del análisis de contenido. El desempeño del psicólogo se retrata desde una perspectiva institucional y crítica, destacando la promoción de eventos, noticias sobre la creación de la Asociación Brasileña de PEE y la referencia a profesionales de MG que contribuyeron al área. Los años 1999 a 2004 fueron los más productivos en términos de publicaciones, corroborando la producción académica crítica del momento. La disminución en los años siguientes está relacionada con la defensa del psicólogo como profesional de la salud. Las gestiones del CRP influyen en el periódico, pero, en general, la PEE es menos citada que otros temas, como la salud mental y la reforma psiquiátrica. Referencias a la Educación se basan en los Derechos Humanos y en la idea de la escuela democrática. El periódico cumple el papel de tratar las prácticas psicológicas en Educación en una perspectiva contraria a la actuación individualizante y modelo médico clínico, sin embargo, necesita una mayor difusión del PEE para fortalecer la imagen del psicólogo como agente de transformación de la escuela. (AU)

Molecular characterization and sequecing analysis of SARS-CoV-2 genome in Minas Gerais, Brazil.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in Wuhan, China, is the causative agent of the coronavirus disease 2019 (COVID-19). Since its first notification in São Paulo state (SP) on 26th February 2020, more than 22,300,000 cases and 619,000 deaths were reported in Brazil. In early pandemic, SARS-CoV-2 spread locally, however, over time, this virus was disseminated to other regions of the country. Herein, we performed genomic sequencing and phylogenetic analysis of SARS-CoV-2 using 20 clinical samples of COVID-19 confirmed cases from 9 cities of Minas Gerais state (MG), in order to evaluate the molecular properties of circulating viral strains in this locality from March to May 2020. Our analyses demonstrated the circulation of B.1 lineage isolates in the investigated locations and nucleotide substitutions were observed into the genomic regions related to important viral structures. Additionally, sequences generated in this study clustered with isolates from SP, suggesting a dissemination route between these two states. Alternatively, monophyletic groups of sequences from MG and other states or country were observed, indicating independent events of virus introduction. These results reinforce the need of genomic surveillance for understand the ongoing spread of emerging viral pathogens.

Nicotianagandarela (Solanaceae), a new species of 'tobacco' highly endangered from the Quadrilátero Ferrífero in Brazil.

Nicotianagandarela Augsten & Stehmann (Solanaceae), sp. nov., a small 'tobacco' known only from one locality at Serra do Gandarela, in the state of Minas Gerais, Brazil, is described and illustrated. It is morphologically characterized by its rosulate basal leaves, red corolla with a short tube not inflated at the apex, and the peculiar habitat, a shaded site under a rocky outcrop ledge along a forested stream. Phylogenetic analyses based on a combined dataset of nuclear (ITS) and plastid (ndhF, trnLF, and trnSG) DNA sequences revealed that the species belongs to the Nicotianasect.Alatae and is sister to the clade with the remaining species in the section. A key for the identification of Brazilian species of the section is given. The unusual habitat, the small population size, and the intense pressure of mining activities in the surroundings made the species assessed as Critically Endangered (CR), needing conservation efforts to avoid its extinction.

Políticas culturais de Lazer e Esporte nas universidades de Minas Gerais: os casos da CEL/UFLA, CEU/UFMG, DIESU/UFU e DLZ/UFV / Leisure and Sport cultural policies at the federal universities of Minas Gerais: the case of CEL/UFLA, CEU/UFMG, DIESU/UFU and DLZ/UFV / Políticas culturales de Ocio y Deporte en las universidades federales de Minas Gerais: los casos de CEL/UFLA, CEU/UFMG, DIESU/UFU y DLZ/UF

O objetivo do estudo foi compreender em que medida a existência da Coordenadoria de Esporte e Lazer (CEL) da UFLA, do Centro Esportivo Universitário (CEU) da UFMG e da Divisão de Esporte e Lazer Universitário (DIESU) da UFU pode contribuir para o desenvolvimento sistemático de políticas de lazer e esporte nas universidades mineiras. Foi utilizada uma pesquisa documental de caráter exploratório descritivo dos Regimentos, Resoluções e Regulamentos Internos, desenvolvida à luz da proposta teóricometodológica do Ciclo Político. Destaca-se que estes órgãos apresentaram definições de orientações normativas de alcance, de conteúdo, dos programas, assim como estruturas organizacionais próprias, configurando a existência de uma política institucional destinada ao lazer e ao esporte (AU).

The aim of the study was to understand in what way the existence of the Coordination of Sport and Leisure (CEL) at UFLA, the University Sports Center (CEU) at UFMG and the Division of University Sport and Leisure (DIESU) at UFU can contribute to development systematic of leisure and sport policies in Minas Gerais universities. A documentary research of descriptive exploratory character of the Internal Regiments, Resolutions and Regulations was used and developed in the light of the theoretical methodological proposal of the Police Cycle. It is noteworthy that these bodies presented definitions of normative guidelines, scope, content, programs, as well as their own organizational structures configuring the existence of an institutional policy aimed at leisure and sport

El objetivo del estudio fue comprender si la existencia de la Coordinación de Deporte y Ocio (CEL/UFLA), el Centro Deportivo Universitario (CEU/UFMG) y la División de Deporte y Ocio Universitario (DIESU/UFU) pueden contribuir al desarrollo sistemático de políticas de ocio y deporte en las universidades de Minas Gerais. Se utilizó una investigación documental de carácter descriptivo exploratorio del Regimientos, Resoluciones y Reglamentos Internos, desarrollado a la luz de la propuesta teórica metodológica del Ciclo Político. Es de destacar que estos órganos presentaron definiciones de lineamientos normativos, alcances, contenidos, programas, así como sus propias estructuras organizativas configurando la existencia de una política institucional orientada al ocio y al deporte

Políticas culturais de Lazer e Esporte nas universidades de Minas Gerais: os casos da CEL/UFLA, CEU/UFMG, DIESU/UFU e DLZ/UFV / Leisure and Sport cultural policies at the federal universities of Minas Gerais: the case of CEL/UFLA, CEU/UFMG, DIESU/UFU and DLZ/UFV / Políticas culturales de Ocio y Deporte en las universidades federales de Minas Gerais: los casos de CEL/UFLA, CEU/UFMG, DIESU/UFU y DLZ/UFV

O objetivo do estudo foi compreender em que medida a existência da Coordenadoria de Esporte e Lazer (CEL) da UFLA, do Centro Esportivo Universitário (CEU) da UFMG e da Divisão de Esporte e Lazer Universitário (DIESU) da UFU pode contribuir para o desenvolvimento sistemático de políticas de lazer e esporte nas universidades mineiras. Foi utilizada uma pesquisa documental de caráter exploratório descritivo dos Regimentos, Resoluções e Regulamentos Internos, desenvolvida à luz da proposta teórico metodológica do Ciclo Político. Destaca-se que estes órgãos apresentaram definições de orientações normativas de alcance, de conteúdo, dos programas, assim como estruturas organizacionais próprias, configurando a existência de uma política institucional destinada ao lazer e ao esporte.

The aim of the study was to understand in what way the existence of the Coordination of Sport and Leisure (CEL) at UFLA, the University Sports Center (CEU) at UFMG and the Division of University Sport and Leisure (DIESU) at UFU can contribute to development systematic of leisure and sport policies in Minas Gerais universities. A documentary research of descriptive exploratory character of the Internal Regiments, Resolutions and Regulations was used and developed in the light of the theoretical methodological proposal of the Police Cycle. It is noteworthy that these bodies presented definitions of normative guidelines, scope, content, programs, as well as their own organizational structures configuring the existence of an institutional policy aimed at leisure and sport.

El objetivo del estudio fue comprender si la existencia de la Coordinación de Deporte y Ocio (CEL/UFLA), el Centro Deportivo Universitario (CEU/UFMG) y la División de Deporte y Ocio Universitario (DIESU/UFU) pueden contribuir al desarrollo sistemático de políticas de ocio y deporte en las universidades de Minas Gerais. Se utilizó una investigación documental de carácter descriptivo exploratorio del Regimientos, Resoluciones y Reglamentos Internos, desarrollado a la luz de la propuesta teórica metodológica del Ciclo Político. Es de destacar que estos órganos presentaron definiciones de lineamientos normativos, alcances, contenidos, programas, así como sus propias estructuras organizativas configurando la existencia de una política institucional orientada al ocio y al deporte.

Systematics of the Trembleya sensu stricto clade of Microlicia (Melastomataceae, Lavoisiereae).

A systematic monograph of the Trembleya s.s. clade is presented, a Brazilian endemic lineage of Melastomataceae comprising 11 species and currently recognised as part of Microlicia s.l. (Melastomataceae). First, we investigate phylogenetic relationships within Lavoisiereae using two nuclear markers and two sampling datasets (102 and 134 terminals). Then, we provide a systematic revision and new circumscription of the Trembleya s.s. clade, including line drawings, photos of living specimens, leaves and floral parts, distribution maps, a key to the 11 accepted species, comments on morphology, reproductive biology, richness, endemism, biogeography and recommended conservation assessments. A nomenclatural update of all taxa previously treated in Trembleya is also provided, including the designation of 45 lectotypes and the proposal of 38 new synonyms.

Temporal trends in the epidemiology of inflammatory bowel diseases in the public healthcare system in Brazil: A large population-based study.

Background: Population-based data on epidemiology of Inflammatory Bowel Diseases (IBD) in Brazil are scarce. This study aims to define temporal trends of incidence and prevalence rates of Crohn's disease (CD) and ulcerative colitis (UC) in Brazil. Methods: All IBD patients from the public healthcare national system were included from January 2012 to December 2020. Average Annual Percent Change (AAPC) and 95% confidence intervals (CI) were calculated using log-linear regression for incidence and binomial regression for prevalence. Moran's I autocorrelation index was used to analyse clustering of cities by level of prevalence. Findings: A total of 212,026 IBD patients were included. Incidence of IBD rose from 9.4 in 2012 to 9.6 per 100,000 in 2020 (AAPC=0.8%; 95% CI -0.37, 1.99); for UC, incidence increased from 5.7 to 6.9 per 100,000 (AAPC=3.0%; 95% CI 1.51, 4.58) and for CD incidence decreased from 3.7 to 2.7 per 100,000 (AAPC=-3.2%; 95% CI -4.45, -2.02). Prevalence of IBD increased from 30.0 in 2012 to 100.1 per 100,000 in 2020 (AAPC=14.8%; CI 14.78-14.95); for UC, from 15.7 to 56.5 per 100,000 (AAPC=16.0%; CI 15.94, 16.17); for CD from 12.6 to 33.7 per 100,000 (AAPC=12.1% CI 11.95, 12.02). A south-north gradient was observed in 2020 prevalence rates of IBD [I=0.40 (p<0.0001)], CD [I=0.22 (p<0.0001)] and UC [I=0.42 (p<0.0001)]. Interpretation: Incidence of CD is decreasing whereas of UC is increasing, leading to stabilization in the incidence of IBD from 2012 to 2020 in Brazil. Prevalence of IBD has been climbing with 0.1% of Brazilians living with IBD in 2020. Funding: None.

Profile of hospitalization and death records associated to dengue and severe dengue in Minas Gerais between 2000 and 2015 from the Brazilian Public Health System perspective.

BACKGROUND & OBJECTIVES: Dengue is one of the most important arboviruses and public health problem associated with increasingly large outbreaks, especially in tropical countries such as Brazil. The state of Minas Gerais, in particular, has had high numbers of cases of this infection in recent years. METHODS: Our study evaluated the epidemiological impact of dengue fever in the state of Minas Gerais from the National Health System (Sistema Único de Saúde, SUS) perspective between 2000 to 2015 using the Brazilian Notifiable Diseases Information System (SINAN, notification cases) and Hospital Information System (SIH)/SUS (hospitalization registers) databases. RESULTS: The SUS database recorded 34,996 reports of dengue (International Classification of Diseases [ICD]: A90) as well as 1984 verified cases of severe dengue (ICD-A91). These hospitalizations for dengue and cases of severe dengue generally affected individuals aged 15-24 (17.74%) and 5-14 (20.86%) years, respectively. The epidemiological burden of dengue was substantial in Minas Gerais state, with the highest number of notifications nationally in 2013. INTERPRETATION & CONCLUSION: From retrospective data associated with dengue records, our study sought to better highlight the locations with the largest number of dengue cases in the Minas Gerais state, and contribute to direct educational and surveillance actions of these regions applied to this infection.

Microliciadeflexa and M.johnwurdackiana (Melastomataceae), two new species from the Brazilian Cerrado.

Microliciadeflexa sp. nov. and M.johnwurdackiana sp. nov. are described, illustrated and an updated identification key for the species of Microlicia from Clube Caça e Pesca Itororó de Uberlândia is provided. Microliciadeflexa occurs in Minas Gerais and Goiás States and is characterised by its linear-lanceolate and deflexed sepal on flower and immature fruit, long pedicel and indumentum of glandular trichomes, mixed with spherical, golden glands. Microliciajohnwurdackiana is endemic to Uberlândia and characterised by having indumentum of setose trichomes and spherical, golden glands, magenta petal with greenish abaxial surface at the apex and dimorphic stamens with bicolorous and tetrasporangiate anthers.

AbstractMicroliciadeflexa sp. nov. e M.johnwurdackiana sp. nov. são descritas, ilustradas e uma chave de identificação atualizada para as espécies de Microlicia do Clube Caça e Pesca Itororó de Uberlândia é fornecida. Microliciadeflexa ocorre nos estados de Minas Gerais e Goiás, e é caracterizada pela sépala linear-lanceolada e deflexa na flor e no fruto imaturo, pedicelo longo e indumento com tricomas glandulares misturados com glândulas esféricas, douradas. Microliciajohnwurdackiana é endêmica de Uberlândia, e caracterizada pelo indumento de tricomas setosos e glândulas esféricas, douradas, pétala magenta com a face abaxial esverdeada apenas no ápice e estames dimórficos com anteras bicolores e tetraesporangiadas.

Epidemiology and evolution of Zika virus in Minas Gerais, Southeast Brazil.

Autochthonous Zika virus (ZIKV) transmission in Brazil was first identified in April 2015 in Brazil, with the first ZIKV-associated microcephaly cases detected in October 2015. Despite efforts on understanding ZIKV transmission in Brazil, little is known about the virus epidemiology and genetic diversity in Minas Gerais (MG), the second most populous state in the country. We report molecular and genomic findings from the main public health laboratory in MG. Until January 2020, 26,817 ZIKV suspected infections and 86 congenital syndrome cases were reported in MG state. We tested 8552 ZIKV and microcephaly suspected cases. Ten genomes were generated on-site directly from clinical samples. A total of 1723 confirmed cases were detected in Minas Gerais, with two main epidemic waves; the first and larger epidemic wave peaked in March 2016, with the second smaller wave that peaked in March 2017. Dated molecular clock analysis revealed that multiple introductions occurred in Minas Gerais between 2014 and 2015, suggesting that the virus was circulating unnoticed for at least 16 months before the first confirmed laboratory case that we retrospectively identified in December 2015. Our findings highlight the importance of continued genomic surveillance strategies combined with traditional epidemiology to assist public health laboratories in monitoring and understanding the diversity of circulating arboviruses, which might help attenuate the public health impact of infectious diseases.

Regional inequalities in cervical cancer survival in Minas Gerais State, Brazil.

BACKGROUND: Cervical cancer survival is marked by socioeconomic and demographic inequalities. We investigated differences in survival across health regions in Minas Gerais, Brazil, in cervical cancer patients who underwent treatment in the Brazilian Public Health System. METHODS: From a database developed through probabilistic and deterministic linkage of data from information systems of the Brazilian Public Health System, we identified cervical cancer cases, diagnosed between 2002 and 2010, who underwent radiation and/or chemotherapy and lived in Minas Gerais, Brazil. Five-year overall and cause-specific survivals were estimated by the Kaplan-Meier method and compared using the log-rank test. We used extended Cox models to assess the relationship between the health region of residence and the overall and cause-specific death risk, adjusting for relevant variables. RESULTS: We included 5613 patients with a median age of 55.0 years. Median follow-up time was 70.0 months. Five-year overall and cause-specific survivals were 56.3 % and 63.6 %, respectively. Across the 13 health regions, 5-year survival ranged from 46.6%-64.2% (p < 0.001) in the overall analysis and from 52.0% to 72.0% (p < 0.001) in the cause-specific analysis. Multivariate models revealed a significantly higher death risk for most health regions in comparison to the reference health region (Norte). Adjustment by age, tumor stage, comorbidity, treatment, travel time, and year of diagnosis had little effect on the association. CONCLUSION: We found regional disparities in cervical cancer survival that persisted after relevant adjustments. Uneven regional provision of health services might be implicated in these disparities, affecting timely access to treatment for cervical cancer patients.

Impact of COVID-19 in Minas Gerais, Brazil: Excess deaths, sub-notified cases, geographic and ethnic distribution.

By analysing the evolution of the COVID-19 epidemic in the state of Minas Gerais, Brazil, we showed the importance of considering the sub-notification not only of deaths but also of infected cases. It was shown that the largely used criteria of a historical all-deaths baseline are not approachable in this case, where most of the deaths are associated with causes that should decrease due to social distancing and reduction of economic activities. A quite simple and intuitive model based on the Gompertz function was applied to estimate excess deaths and excess of infected cases. It fits well the data and predicts the evolution of the epidemic adequately. Based on these analyses, an excess of 21.638 deaths and 557.216 infected cases is predicted until the end of 2020, with an upper bound of the case fatality rate of around 2.4% and a prevalence of 2.6%. The geographical distribution of cases and deaths and its ethnic correlation are also presented. This study points out the necessity of governmental and private organizations working together to improve public awareness and stimulate social distancing to curb the viral infection, especially in critical places with high poverty.

Evaluation of actions of the official veterinary service to mitigate outbreaks of infectious laryngotracheitis and improve biosecurity on laying hen farms / Avaliação de ações do serviço veterinário oficial para bloqueio de foco de laringotraqueite infecciosa e melhoria da biosseguridade em granjas de postura

Infectious laryngotracheitis (ILT), caused by an Alphaherpesvirus (Gallid herpesvirus-1; GaHV-1), has been noticed in the region of the Terras Altas da Mantiqueira, Minas Gerais. From 2010 to 2018, the "Serviço Veterinário Oficial" (SVO) of the "Instituto Mineiro Agropecuário" (IMA), implemented measures to prevent spread of the virus to other regions and control the disease in the area. Due to the close proximity and consequent epidemiological link among farms, the region was considered a unique epidemiological unit. To check the efficiency of the ILT control measures, we carried out: (1) a seroepidemiological survey, (2) questionnaires for evaluating biosecurity measures; and (3) an evaluation of the influence of farm population density on the occurrence of ILT. In 2016, 2017, and 2018, ILT was investigated using epidemiological and clinicopathological methods, along with GaHV-1 molecular detection. Serological survey was carried out on 24 farms in the quarantined region and on 13 farms from other regions of the state. In 2010 and 2018, questionnaires were applied to collect data and determine indicators of biosecurity practices in all farms of the quarantined area. The differences were then assessed (Wilcoxon's p<0.05). The results indicated positive serology throughout the region, although only on four farms (16.6%) the chickens have clinical signs, macroscopic and histological lesions of ILT. The prevalence of viral infection increased from 2016 (27%) to 2017 (50%) and was higher in farms with a high stock density (p=0.033). No disease, virus or antibodies were detected in the farms outside of the quarantined area. Although the biosecurity indicators had improved on all farms in the quarantined area (p<0.05), the virus was active and circulating in the region. The contingency measures have contained the outbreak, but biosecurity practices are paramount in the control of new outbreaks. Official control will be maintained in the region, including surveillance of new cases and biosecurity procedures to mitigate the risk of the virus reaching other regions.(AU)

Laringotraqueíte infecciosa (LTI), causada por um alfaherpesvírus (herpesvírus Gallid-1; GaHV-1), foi observada na região das Terras Altas da Mantiqueira, Minas Gerais. De 2010 a 2018, o Serviço Veterinário Oficial (SVO) do Instituto Mineiro Agropecuário (IMA) implementou medidas para impedir a disseminação do vírus para outras regiões do estado e controlar a doença na região interditada. Devido à proximidade e consequente vínculo epidemiológico entre as granjas, a região foi considerada uma unidade epidemiológica única. Para verificar a eficiência das medidas de controle de LTI, foram realizados: (1) pesquisa soroepidemiológica, (2) questionários para avaliar medidas de biosseguridade; e (3) avaliação da influência da densidade populacional da granja na ocorrência de LTI. Em 2016, 2017 e 2018, a LTI foi investigada usando métodos epidemiológicos e clínico-patológicos, com a detecção molecular de GaHV-1. O levantamento sorológico foi realizado em 24 granjas da região interditada e em 13 granjas de outras regiões do estado. Em 2010 e 2018, foram aplicados questionários para coletar dados e determinar indicadores de medidas de biosseguridade em todas as granjas da área interditada. As diferenças foram avaliadas (p<0,05 de Wilcoxon). Os resultados indicaram sorologia positiva em toda a região, embora apenas em quatro granjas (16,6%) as galinhas apresentaram sinais clínicos, lesões macroscópicas e histológicas da LTI. A prevalência de infecção viral aumentou de 2016 (27%) para 2017 (50%) e foi maior em fazendas com alta densidade de alojamento (p=0,033). Presença da doença, vírus ou anticorpos foram detectados nas granjas fora da área interditada. Embora os indicadores de biosseguridade tenham melhorado em todas as fazendas da área interditada (p<0,05), o vírus está ativo e circulava na região. As medidas de contingência contiveram o surto, mas as práticas de biosseguridade são fundamentais para o controle de novos surtos. O controle oficial será mantido na região, incluindo a vigilância de novos casos e procedimentos de biosseguridade para mitigar o risco de transmissão do vírus para outras regiões.(AU)

Evaluation of actions of the official veterinary service to mitigate outbreaks of infectious laryngotracheitis and improve biosecurity on laying hen farms

ABSTRACT: Infectious laryngotracheitis (ILT), caused by an Alphaherpesvirus (Gallid herpesvirus-1; GaHV-1), has been noticed in the region of the Terras Altas da Mantiqueira, Minas Gerais. From 2010 to 2018, the Serviço Veterinário Oficial (SVO) of the Instituto Mineiro Agropecuário (IMA), implemented measures to prevent spread of the virus to other regions and control the disease in the area. Due to the close proximity and consequent epidemiological link among farms, the region was considered a unique epidemiological unit. To check the efficiency of the ILT control measures, we carried out: (1) a seroepidemiological survey, (2) questionnaires for evaluating biosecurity measures; and (3) an evaluation of the influence of farm population density on the occurrence of ILT. In 2016, 2017, and 2018, ILT was investigated using epidemiological and clinicopathological methods, along with GaHV-1 molecular detection. Serological survey was carried out on 24 farms in the quarantined region and on 13 farms from other regions of the state. In 2010 and 2018, questionnaires were applied to collect data and determine indicators of biosecurity practices in all farms of the quarantined area. The differences were then assessed (Wilcoxons p 0.05). The results indicated positive serology throughout the region, although only on four farms (16.6%) the chickens have clinical signs, macroscopic and histological lesions of ILT. The prevalence of viral infection increased from 2016 (27%) to 2017 (50%) and was higher in farms with a high stock density (p=0.033). No disease, virus or antibodies were detected in the farms outside of the quarantined area. Although the biosecurity indicators had improved on all farms in the quarantined area (p 0.05), the virus was active and circulating in the region. The contingency measures have contained the outbreak, but biosecurity practices are paramount in the control of new outbreaks. Official control will be maintained in the region, including surveillance of new cases and biosecurity procedures to mitigate the risk of the virus reaching other regions.

RESUMO: Laringotraqueíte infecciosa (LTI), causada por um alfaherpesvírus (herpesvírus Gallid-1; GaHV-1), foi observada na região das Terras Altas da Mantiqueira, Minas Gerais. De 2010 a 2018, o Serviço Veterinário Oficial (SVO) do Instituto Mineiro Agropecuário (IMA) implementou medidas para impedir a disseminação do vírus para outras regiões do estado e controlar a doença na região interditada. Devido à proximidade e consequente vínculo epidemiológico entre as granjas, a região foi considerada uma unidade epidemiológica única. Para verificar a eficiência das medidas de controle de LTI, foram realizados: (1) pesquisa soroepidemiológica, (2) questionários para avaliar medidas de biosseguridade; e (3) avaliação da influência da densidade populacional da granja na ocorrência de LTI. Em 2016, 2017 e 2018, a LTI foi investigada usando métodos epidemiológicos e clínico-patológicos, com a detecção molecular de GaHV-1. O levantamento sorológico foi realizado em 24 granjas da região interditada e em 13 granjas de outras regiões do estado. Em 2010 e 2018, foram aplicados questionários para coletar dados e determinar indicadores de medidas de biosseguridade em todas as granjas da área interditada. As diferenças foram avaliadas (p 0,05 de Wilcoxon). Os resultados indicaram sorologia positiva em toda a região, embora apenas em quatro granjas (16,6%) as galinhas apresentaram sinais clínicos, lesões macroscópicas e histológicas da LTI. A prevalência de infecção viral aumentou de 2016 (27%) para 2017 (50%) e foi maior em fazendas com alta densidade de alojamento (p=0,033). Presença da doença, vírus ou anticorpos foram detectados nas granjas fora da área interditada. Embora os indicadores de biosseguridade tenham melhorado em todas as fazendas da área interditada (p 0,05), o vírus está ativo e circulava na região. As medidas de contingência contiveram o surto, mas as práticas de biosseguridade são fundamentais para o controle de novos surtos. O controle oficial será mantido na região, incluindo a vigilância de novos casos e procedimentos de biosseguridade para mitigar o risco de transmissão do vírus para outras regiões.